Pause Slideshow

Stay Healthy with Resveratrol

altNamed as everything from a miracle cure for obesity, a source for eternal youth, and an explanation for the so-called French paradox, resveratrol has been the focus of a lot of buzz for several years now.1 Resveratrol is a polyphenol called a stilbene found in many plants, especially in those plants containing a natural deep purplish hue.2 It’s the grape skins that give red wine high levels of resveratrol, which may explain the seeming paradox between a high-fat, wine-loving French diet and their relatively low rates of heart disease.3 And surely every chocolate lover will be a resveratrol devotee when they learn that chocolate ranks second after red wines and grape juice in terms of resveratrol content.4

Resveratrol News Flash!

Lozenges May Increase Resveratrol's Bioavailability

Could lozenges be a better way to get your daily dose of resveratrol? Preliminary clinical research by a lab in San Antonio, Texas hints they might be. Results suggest lozenges could help overcome perceived limitations of oral resveratrol supplements. (277)

Faster Delivery

In the study, two healthy male volunteers in their early thirties were each given one hard lozenge to take (similar to a cough drop or piece of small hard candy). The 2000-mg lozenges contained 8% resveratrol dissolved in sugar, for about 146 mg of resveratrol per piece. (277)

Peak levels of resveratrol were reached in the blood within 15 minutes. More importantly, the levels of non-metabolized resveratrol were much greater than those found in similar doses of resveratrol supplements that are swallowed. (277)

Why is Bioavailability Important?

Animal and human clinical studies suggest that resveratrol is good for heart health and metabolism. It also has anti-inflammatory effects. (277)

However, once swallowed, how much resveratrol actually gets into the bloodstream after breaking down in the digestive system isn't very much. This has led to concerns about resveratrol's low bioavailability. In other words, experts wonder if there's even enough resveratrol left in its whole form to have a therapeutic effect. (277)

Some animal studies indicate that resveratrol metabolites are also beneficial and may convert back to resveratrol afterwards (before being excreted). But the evidence isn't conclusive, so scientists have been trying to find ways to improve resveratrol's bioavailability. (277)

Lozenges Produce Higher Plasma Levels

Much higher peak levels of resveratrol in the blood were found in both volunteers who participated in this recently-published study. Blood tests showed that maximum levels from the lozenges were over 12 times higher than average peak levels shown in other research using 200-mg oral resveratrol supplements. (277)

Take-Away Point

The authors caution that this was only a proof-of-concept study. Still, the findings suggest that lozenges could help improve bioavailability of resveratrol - ostensibly increasing its healthful benefits. (277)

Related News...

  • Book Review: The Homebrew Industrial Revolution (2010)

    h+ Media 3 Aug 2016 | 6:24 am

    Author Harry J. Bentham       Predicting an economic “singularity” approaching, Kevin Carson from the Center for a Stateless Society writes in The Homebrew Industrial Revolution (2010) we can look forward to a vibrant “alternative economy” driven less and less by[…]   Read more...

  • Prospective Longevity R&D Program in Kazakhstan

    h+ Media 6 Jun 2016 | 6:03 am

    Potential establishment of a state program in Kazakhstan to improve the healthspan of the population. On May 19, 2016, the World Health Organization released its report “World Health Statistics: Monitoring Health for the Sustainable Development Goals (SDGs)”, describing the recent[…]   Read more...

  • Zebrafish prefer lookalike robots with the right moves

    Futurity 25 Oct 2016 | 9:22 am

    A new study suggests zebrafish engage more with 3D-moving robotic models of themselves than with other stimuli. Scientists devised a controllable, customizable robotic platform to help them more accurately study freshwater fish behavior. Like a puppet master, the robotic platform[…]   Read more...

  • Even 1 tree adds biodiversity to in-between areas

    Futurity 25 Oct 2016 | 9:17 am

    On a gradient from pristine wilderness to a parking lot, most species live somewhere in between. Protecting species in these in-between areas is a challenge because there’s no way to measure biodiversity without time-consuming field surveys. With no way to[…]   Read more...

  • Should breast cancer tests include prolactin?

    Futurity 25 Oct 2016 | 11:33 am

    Screening breast cancer patients for the prolactin receptor could improve the prognosis for patients and may help them avoid unnecessary and invasive treatments, say researchers. Using a database of 580 women with triple negative breast cancer (TNBC), the researchers found[…]   Read more...

Disclaimer: This website is not intended to replace professional consultation, diagnosis, or treatment by a licensed physician. If you require any medical related advice, contact your physician promptly. Information at Resveratrol.com is exclusively of a general reference nature. Do not disregard medical advice or delay treatment as a result of accessing information at this site.
Components of plants that can influence physiological and
cellular activity in humans and animals.